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Los Angeles, CA (Sports Network) - Houston Rockets guard James Harden will miss Wednesday's matchup with the Los Angeles Clippers because of several injuries.

It is Houston's final game before the All-Star break.

Harden, who was already dealing with a bruised left knee, tweaked his ankle in the third quarter of Tuesday's win over the Golden State Warriors.

The All-Star guard suffered the injury after landing on the ankle of Warriors forward David Lee on a fast break layup.

Harden finished the contest, but there was reportedly swelling following the game.

Over 53 games this season, Harden is averaging career-highs with 26.1 points, 5.7 assists and 4.8 rebounds per game.