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(Sports Network) - Recent free-agent signee Kyle Lohse makes his second start for his new team on Wednesday night when the Milwaukee Brewers visit Wrigley Field to close out a three-game series with the Chicago Cubs.

Lohse, who'll turn 35 later this year, signed a three-year deal worth $33 million on March 25, making the Brewers his fifth team in a career that began in 2001 and has since included 356 appearances.

He pitched with the Minnesota Twins from 2001 through 2006, spent the end of the 2006 season and the beginning of 2007 with Cincinnati, ended 2007 with Philadelphia and was with the St. Louis Cardinals from 2008 through 2012.

Lohse was 16-3 across 33 starts for St. Louis in his final season there, notching career-highs in wins and innings pitched (211) while posting a 2.86 earned run average.

He debuted with the Brewers on April 5 and took a tough luck 3-1 loss to Arizona after allowing a run on five hits in six innings.

In 16 career starts against the Cubs, he's 4-4 with a 5.17 ERA.

Chicago goes with 6-foot-7 righty Scott Feldman, who'll also make his second start with a new team.

The 30-year-old was drafted in 2003 by the Texas Rangers and made 204 appearances with them through 2012, including a career-best 17-win season in 2009.

He won just six times in 17 decisions last season before becoming a free agent and signing a one-year deal worth $6 million.

Feldman dropped a 4-1 decision in Atlanta in his first National League start on April 5 after allowing four runs and five hits in 4 2/3 innings.

He won his lone career start against the Brewers.

On Tuesday, Scott Hairston's sacrifice fly broke a tie game and the Cubs scored three runs in the eighth to take a 6-3 victory. David DeJesus went 3- for-5, scored twice and his two-run single gave the Cubs a three-run cushion.

Newly anointed closer Kyuji Fujikawa then worked out of trouble in the ninth to notch his second save.

Anthony Rizzo knocked in a pair of runs and Cubs starter Travis Wood settled in to throw 6 1/3 innings of three-run ball on six hits with five strikeouts.

Carlos Marmol (1-1), who was removed from his role as closer, pitched a scoreless eighth to earn the win.

Chicago manager Dale Sveum is hoping the move will help his confidence.

"We're just getting him into more comfortable situations, where you don't have to deal with the stress of those last three outs," said Sveum.

After a miserable first outing, Wily Peralta bounced back with a solid performance, but John Axford (0-2) was touched for three runs on two walks and a hit in the eighth. Peralta surrendered three runs -- two earned -- on six hits with five strikeouts over 6 2/3 innings of work.

Ryan Braun and Jean Segura both went 2-for-4 with an RBI for the Brewers, who had snapped a five-game losing streak with a 7-4 win on Monday against the Cubs.

The Brewers won 13 of 17 games in the head-to-head series in 2012, including six of eight at Wrigley Field.

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